MadSci Network: Biochemistry

Re: Is catalase the same thing as Hydrogen peroxidase?

Date: Wed Oct 13 10:03:50 1999
Posted By: Michael Onken, MadSci Admin
Area of science: Biochemistry
ID: 939770272.Bc

Yes and no.

Catalase is a member of the peroxidase family that specifically uses hydrogen peroxide as a substrate, hence it could be called "Hydrogen Peroxidase": however, so does Peroxidase (also called Myeloperoxidase). The major difference between Catalase and Peroxidase is that Catalase generates water and Oxygen, while Peroxidase generates water and an activated donor molecule. So "Hydrogen Peroxidase" could actually refer to more than one enzyme without identifying the more important aspect of the reaction: where the free radical goes. For this reason, the name "Hydrogen Peroxidase" is not accepted by the international scientific community.

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